Karen J. Lewis entered Heaven on Feb. 24, 2025. She was born to Floyd and Bertha (Chastain) Pennington on July 24, 1939. She married William “Willie” T. Lewis on Feb. 25, 1957. Together they had 5 children. Karen enjoyed spending time with family and having coffee with friends. She is Survived by two sons, Stanley and wife Tomasa Lewis, Donald and wife Michelle Lewis, two daughters, Debra and husband Bryan Lewis, and Mary and husband Bobby Duke. 15 grandchildren and 20 great-grandchildren. And many family and friends that will miss her dearly. She was preceded in death by husband, William T. Lewis and one son, William D. Lewis. Graveside services will be held March 8, 2025 at Reeds Cemetery, Reeds, MO. Arrangements are under the direction of Ozark Memorial Park Crematory, Joplin, MO